He currently plays for Internacional de Bogota (W), wearing the number 19 shirt. He plays primarily as a Defender. He stands at 163cm tall and weighs 49kg.

Throughout the Colombian Liga Betplay Femenina 2026, Maria Jose Guisamano Mercado featured in 2 matches, averaging 0 tackles, 0 interceptions, and 0 clearances per game, while blocking 0 shots per game.